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KMID : 1189419880010010001
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Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology
1988 Volume.1 No. 1 p.1 ~ p.14
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Experimental Studies on the Anti-inflammatory, Analgesic Effects of Pilyongbangkamgil-Tang and Kamipilyongbangkamgil-Tang on Rats and Mice
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Park Hang-Gi
Chae Byung-Yoon
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Abstract
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According to oriental clinic effect findings hitherto, Pilyongbangkamgil-Tang has been curative effects on chronic pharnygitis, acute tensillitis and angina. Auther tried to make clear the anti-inflammatory effect on rat paw which has become edema formation by 5% of acetic acid／saline solution, and the analgesic effect on mouse thorough method of acetic acid because the medicine decoction of Kamipilyongbangkamgil-Tang, Pilyongbangkamgil-Tang, and the extracted powder of Pilyongbangkamgil-Tang are administered to rat and mouse. In present report, anti-inflammatory, analgesic effect of Pilyongbangkamkil-Tang, the extracted powder of the above prescription and Kamipilyongbangkamgil-Tang were estimated by the above test. The results are summarized as follows. 1. Kamipilyongbangkamgil-Tang (liquid), Pilyongbangkamgil-Tang and the extracted powder of Pilyongbangkamgil-Tang were tested for analgesic effects; Kamipilyongbangkamgil-Tang has the most effective analgesic function, then Pilyongbangkamgil-Tang, then the extracted powder, and I found that the t-test of those above prescriptions, in this order, should come to the result of voluntariness P〈0.001, P〈0.02, and P〈0.05 respectively. 2. Analgesic effects of pilyongbangkamgil-Tang and the extracted powder against the mouse pain induced by acetic acid have been strengthened by increase of double dosage and 4 fold dosage. 3. With Pilyongbangkamgil-Tang and Kamipilyongbangkamgil-Tang treated for rat, the increasing and the inhibitory rate of rat paw edema formation showed significantly statistical values, and the anti-inflammatory effect of the extracted powder of Pilyongbangkamgil-Tang is not supported so long than Pilyongbangkamgil-Tang. 4. The anti-inflammatory effect of Kamipilyongkamgil-Tang on the edema formed at the rat paw appeared significantly statistical value than the other sample.
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KEYWORD
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